The clubs will play their round 3 match at Dunsborough Playing Fields, the home of the Dunsborough Dung Beetles, on April 8.
Preceding the main event, the Dung Beetles will take on the Margaret River Gropers and the Collie Mongrels will play against the Bunbury Barbarians.
A Wanneroo junior side will also run out against the junior Dung Beetles.
Get in front of tomorrow's news for FREE
Journalism for the curious Australian across politics, business, culture and opinion.
READ NOWMORE: Still no end in sight to Spud Shed’s appeal
MORE: Brazilian trip leads South Perth pair to food truck idea
MORE: Kalamunda Show to debut new attractions and offer ticket discounts
Perth-Bayswater club manager Steve Wharerau said both clubs were looking forward to the trip down South.
“I was asked by the Dunsborough Dung Beetles if we could help them with their capacity to retain their status in South-West rugby,” he said.
“Our relationship goes back 20 years, although it was only recently that we got the request and tried to consolidate it.
“It will be an exercise to start our season off well and broaden our supporter base.”
Wharerau said there would be scope to potentially scout future players from Dunsborough.
“Part of the idea is to attract more players and broaden our supporter base,” he said. “This opens it up to being an annual or maybe a bi-annual event.”