After losing his cousin Tim to acute myeloid leukaemia in January, Mr Williams will combine his love of cycling with his passion for music to fundraise for others living with cancer.
On Saturday night, he and his band Random Axe will host Rock for Cancer at the Railway Hotel, with proceeds to the Ride to Conquer Cancer, which benefits the Harry Perkins Institute of Medical Research, based in Nedlands.
Mr Williams said it will be the third year he has taken part in the ride, having raised more than $100,000 in the first two years.
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READ NOW"It's for Tim and the thousands like him that fight battles with cancer every day, that is why I ride," he said.
"At the start of the ride, there are people telling their stories of survival.
"It's extremely moving and motivating and everyone is so pumped to be involved.
"Having people waving and cheering along the way is really special.
"You get a feel for how much cancer affects so many people and you have an enormous sense of achievement at the end."
Random Axe will perform Rock for Cancer on August 29 at the Railway Hotel.
Visit www.facebook.com/the RandomAxeBand for more information.
The Ride to Conquer Cancer is on October 17 and 18.