The new buildings, which are part funded by a $3.9 million Lotterywest grant announced by Health Minister Kim Hames last week, will house three new Pilatus PC-24 jets, which are expected to be purchased over the coming two years.
The facility will also allow engineers to maintain the aircraft on site, rather than having to outsource that work.
The RFDS helped close to 30,000 people last year.
Dr Hames said the grant would help an organisation that was getting busier all the time.
“This grant will help construct a new hangar and office space, which will undoubtedly enable the organisation to operate more effectively, and provide a greater level of service and health care to West Australians,” he said
The new hangar is expected to be completed by the end of the year.