The duo, who dressed in cat themed clothes throughout November and in the process raised $1545 so far, will host the party at Four5Nine Bar at the Rosemount Hotel in North Perth.
The event will feature musical performances from Simone & Girlfunkle, Mining Tax, Golden String and Hayley Beth.
Guests are encouraged to dress up in a cat costume for the event.
For more details go online here.
SAFE Perth provides shelter, food, de-sexing, microchipping and re-homing for cats and other pets during the lead up to Christmas when most pets are abandoned.
Perth writer and artist Kate-Anna St Valentine started the Meowvember fundraiser in 2011, but died of cancer earlier this year, so her friends picked up where she left off.
To donate to the fundraiser, visit meowvember.tumblr.com/donate .