Award-winning Pyke has been promoting his latest album, The Beginning and the End of Everything.
Mitchell supported the national tour earlier this year of acclaimed fellow singers Neil Finn and Paul Kelly on the back of her second album, Bless This Mess.
The free concert is part of the City’s summer event series, which includes a concert in Yanchep National Park on March 8.
The Pyke-Mitchell concert on November 9, from 4 to 10pm, is free but patrons must register for tickets.
Tickets will be available to City of Wanneroo residents from September 2 and to others on September 23 from the City’s website.