The major prize winner will receive $4000, with the winning artwork added to the city's art collection alongside last year's winning entry, Matthew McAlpine's The Dark Heart of the Land.
The competition is open to upcoming artists and students to encourage and display artistic talent in the south.
"The award is a well established art prize and for over 12 years has provided support and encouragement to many developing artists," City of South Perth Mayor Sue Doherty said.
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READ NOW�The city proudly supports artists and the local art scene by hosting these awards.
"Artists have a great opportunity to showcase their skills and publicly exhibit work."
Limited to one entry an artist, artworks can be 2D, such as paintings or photography, or 3D, such as sculpture.
Entries must be received by 5pm Friday, September18, 2015.
Selected works can be viewed in the City of South Perth Community Hall from October 23 to 31.