Subiaco quickly gained ascendancy by dominating the centre clearances and key forwards Matt Boland and Shane Yarran kicking early goals.
Perth did manage a goal for the term through exciting youngster Marshall Jones, but still trailed the Lions by 19 points at the first change.
The second quarter saw the home side gain complete control of the match, with Sam Menagola and Kyal Horsley picking up possessions at will.
Despite Aidan Tropiano and Michael Sinclair trying hard, Perth simply had few options up forward, as Subiaco kicked seven goals to two to hold a comfortable lead at half-time.
The third quarter saw Subiaco continually entering their forward line, with Boland in particular proving a dangerous opponent for the Perth defenders to shut down.
Perth�s lone key forward Jones bobbed up to boot two goals but the margin at three-quarter time had blown out to an insurmountable 89 points.
The last quarter unfortunately for Perth supporters was much of the same, as Subiaco piled on seven goals for the term, with Boland finishing with seven majors.
Perth could only manage three points, and only had draft prospect Marshall Jones as their sole key forward all day, kicking three goals.
Once again Perth lacked height and experience in most positions around the ground, with Sandover Medal favourite Tropiano picking up 30 possessions, well supported by Sinclair, collecting 29 touches in the midfield.
Next week Perth return home to Lathlain Park on Saturday to play the East Fremantle Sharks.